Job Details - Genomic Analyst-Research Associate - 40140547 | Frederick National Laboratory Talent Network
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Genomic Analyst-Research Associate II in Frederick, MD

Location: Frederick, MD
Career Level: Associate
Industries: Healthcare, Pharmaceutical, Biotech

Description

Genomic Analyst-Research Associate II

Job ID: req2005
Employee Type: exempt full-time
Facility: Frederick: Ft Detrick
Location: PO Box B, Frederick, MD 21702 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

 Position Overview:

PROGRAM DESCRIPTION         

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

The Vaccine, Immunity, and Cancer Directorate (VICD) at the Frederick National Laboratory has a primary mission to provide scientific leadership and laboratory infrastructure to study immune responses to Human Papillomavirus (HPV) vaccines and other cancer preventive strategies in the context of clinical and pre-clinical studies.

KEY ROLES/RESPONSIBILITIES

The Genomic Analyst will:

  • Produce protein antigens through DNA transfection of mammalian cells and purification processes
  • Optimize and validate procedures and methodologies for assessment of immunogenicity of T and B cell responses in mouse in vivo systems
  • Perform immunological assays that may include ELISA, ELISPOT, Luminex assays, flow cytometry, immunohistochemistry
  • Design and implement protocols, with limited supervision, as well as troubleshoot assays independently
  • Evaluate, analyze, and compile data, and maintain databases
  • Responsible for routine QC/QA procedures, ordering supplies, and maintaining equipment, inventories, and lab environment
  • Prepare reports, present data, and participate in manuscript and proposal preparation
  • Remain current on literature and relevant laboratory techniques.

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree.  Foreign degrees must be evaluated for U.S. equivalency
  • In addition to the education requirements, a minimum of five (5) years progressively responsible experience
  • Four (4) years of laboratory bench experience
  • Experience in operating under QC procedures
  • Ability to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration: 

  • Experience in standard cell culture and molecular biology techniques including: aseptic techniques, cell line maintenance, organoid generation and maintenance, western-blot, nucleic acid extraction, and qPCR/rt-qPCR
  • Experience in immunological assays development and validation, include ELISA, ELISPOT, Luminex assays, flow cytometry, immunohistochemistry
  • Experience in fragment analysis, Sanger sequencing or next generation sequencing (NGS)
  • Experience in preclinical/clinical research of vaccines/biologics
  • Knowledge of or experience in cancer biology and immunology and genetically engineered mouse models
  • Experience handling large data sets, statistics, and software tools (Word, Excel, PowerPoint)
  • Experience in Python and R Script
  • Master's Degree

 JOB HAZARDS

  • This position is subject to working with or have potential for exposure to animal(s) and/or animal material(s)
  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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