Job Details - Protein Expression Associate - 40891545 | Frederick National Laboratory Talent Network
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Protein Expression Associate in Frederick, MD

Location: Frederick, MD
Career Level: Associate
Industries: Healthcare, Pharmaceutical, Biotech

Description

Protein Expression Associate

Job ID: req2133
Employee Type: exempt full-time
Facility: ATRF: Other
Location: 8560 Progress Drive, Frederick, MD 21701 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.  The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

 Position Overview:

PROGRAM DESCRIPTION

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research. CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.

KEY ROLES/RESPONSIBILITIES

  • Carry out experiments, under the review of a scientist, in the areas of eukaryotic protein expression
  • Perform cell culture of insect and mammalian cells including cell passaging, cell counting, small/large scale expression, and harvest
  • Carry out small-scale protein purification scouting and large-scale purification from cell culture supernatants
  • Develop and execute technology development projects to support enhanced protein expression
  • Provide timely updates of project progress to supervisor and other staff in both informal and formal reports
  • Maintain detailed records of all laboratory processes and procedures for quality assurance purposes

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in Biology, Chemistry, Biochemistry, or similar field of study or four (4) years relevant experience in lieu of degree.  Foreign degrees must be evaluated for U.S. equivalency
  • In addition to the education requirement, a minimum of two (2) years of related experience
  • Ability to handle multiple scientific projects simultaneously with a high degree of accuracy
  • Laboratory experience with eukaryotic cell culture techniques
  • Ability to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS 

Candidates with these desired skills will be given preferential consideration:

  • Prior experience with recombinant DNA manipulation
  • Prior experience with baculovirus or insect cell protein expression
  • Prior experience in small-scale protein purification
  • Excellent written and verbal communication skills for interactions with team members and collaborators

JOB HAZARDS

  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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