Research Associate I, DOI Support, CGR - ONSITE in Rockville, MD

Description

PROGRAM DESCRIPTION
The Cancer Genomics Research Laboratory (CGR) investigates the contribution of germline and somatic genetic variation to cancer susceptibility and outcomes in support of the NCI's Division of Cancer Epidemiology and Genetics (DCEG), the world's most comprehensive cancer epidemiology research group.  CGR is located at the NCI-Shady Grove campus in Rockville, MD and operated by Leidos Biomedical Research, Inc.  We care deeply about discovering the genetic and environmental determinants of cancer, and new approaches to cancer prevention, through our contributions to the molecular, genetic, and epidemiologic research of the 70+ investigators in DCEG. 

Working in concert with epidemiologists, biostatisticians and basic research scientists in DCEG's intramural research program, CGR provides the capacity to conduct genome-wide discovery studies and targeted regional approaches to identify the heritable determinants of various forms of cancer. This includes the design and analysis of high throughput studies using various types of “–omics” technologies such as array- and sequence-based genome-wide association studies, studies of tumor characteristics using integrated genomic data analysis, and molecular epidemiologic studies based on novel assays focused on the metabolome and microbiome. We are seeking a responsible research associate to join our high-performing team environment to support routine and non-routine customized high-throughput assays and supporting other development efforts as time permits.

KEY ROLES/RESPONSIBILITIES

The CGR's Development, Optimization & Implementation (DOI) team is recruiting for a Research Associate position to support assay development and production efforts. The qualified candidate will have responsibility for executing operational activities including cleaning, setup, and operation of equipment to create a variety of custom assay components (such as synthetic DNA sequences, primers, and barcoded sequencing adapters) required to achieve operational objectives under the direction of senior staff. Key responsibilities include:

• Utilizing good laboratory practices and aseptic laboratory techniques to create reagents, as specified, for in-house developed assays
• Meet expected schedules and performance expectations in a fast-paced research laboratory environment
• Follow established protocols and SOPs and when directed, assist with deviations and corrective actions.
• Accurately maintain thorough documentation and batch records
• Maintain, update and report on physical inventory of raw materials and prepared reagents
• Routine maintenance, operation and troubleshooting of laboratory equipment used
• Support a culture of continuous improvement and accountability
• Support troubleshooting of simple issues associated to processing
• Contribute to process improvement, assay, or process development
• Take on additional tasks or responsibilities to support other development and optimization work when required

BASIC QUALIFICATIONS

 To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Possession of a Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years of experience in lieu of degree
• A minimum of (2) years related biomedical experience
• Must be able to obtain and maintain a clearance
• Experience with aseptic, cleanroom and basic molecular biology techniques
• Technical pipetting accuracy and keen attention to detail
• Ability to perform mathematical calculations
• Strong scientific fundamentals and analytical background
• Aptitude for learning and adhering to standard laboratory procedures as trained
• Attention to detail and ability to independently identify critical variables
• Outstanding communication skills (verbal and written)
• Working knowledge of Windows-based computer operating systems and Microsoft office suite

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:

• Knowledge of GMP or other applicable standards
• Experience with advanced molecular biology techniques (including qPCR, primer design, and NGS library preparation)
• Experience using high-throughput laboratory equipment, such as automated liquid handlers is considered a strong plus including method development.
• Familiarity with eLN and/or LIMS systems
• Bioinformatics and statistics skills, including experience with Python or R
• Experience with reagent/buffer formulation, assay development, microbiology testing and/or HPV typing

JOB HAZARDS

• This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations
• This position may require continuous or intermittent exposure to and exertion in environmental conditions such as working outdoors, temperature extremes, humidity extremes. etc. as part of the job