Research Associate II, Single Cell and Spatial Transcriptomics with Childhood Cancer Data Initiative in Bethesda, MD

Description

PROGRAM DESCRIPTION         

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI's intramural Center for Cancer Research (CCR). The dedicated units provide expertise in electron microscopy, protein characterization, mass spectrometry, protein expression, optical microscopy, and genomics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR), where CRTP scientists work collaboratively with intramural NCI investigators to provide research technologies and expertise.

 KEY ROLES/RESPONSIBILITIES

We are seeking a highly motivated Research Associate to work with the NCI Center for Cancer Research (CCR) Single Cell Analysis Facility (SCAF) to provide dedicated single cell and spatial research support for the intramural Childhood Cancer Data Initiative (CCDI). This will include close collaboration with CCDI Investigators to generate high-quality datasets for multiple projects using established single cell methods and help validate and employ emerging technologies. A major goal of this Initiative is to establish tumor cell atlases for rare pediatric malignancies.

• Providing state-of-the-art single cell and spatial research support to CCDI Investigators
• Performing single cell captures, library preparation, quality control and sequencing
• Processing tissue sections for spatial transcriptomics
• Helping with experimental design, sample preparation and project troubleshooting
• Working to implement support for advanced single cell and spatial methods more efficiently and effectively

**THIS POSITION IS CONTINGENT UPON FUNDING APPROVAL** 

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Possession of a (CHEA) Bachelor's degree from an accredited college or university according to the Council for Higher Education Accreditation. (Additional qualifying experience may be substituted for the required education)
• Five (5) years of experience performing cell and molecular biology experiments
• Familiarity with next generation sequencing methods
• Ability to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS 

Candidates with these desired skills will be given preferential consideration:

• Experience with NextGen library generation, DNA/RNA isolation, and DNA/RNA quantitation
• General cell biology experience, including handling live cells and counting
• Experience working in a core facility or other team-based environment
• Demonstrated ability to learn new technologies quickly
• Knowledge and background experience in cancer biology and immunology
• Must have excellent written and verbal communication skills
• Must be detail-oriented, and able to manage multiple projects simultaneously

JOB HAZARDS

• This position is subject to working with or have potential for exposure to animal(s) and/or animal material(s)
• This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations